CHOLESTEROL

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 Dictionary entry overview: What does cholesterol mean? 

• CHOLESTEROL (noun)
  The noun CHOLESTEROL has 1 sense:

1. an animal sterol that is normally synthesized by the liver; the most abundant steroid in animal tissues

  Familiarity information: CHOLESTEROL used as a noun is very rare.

 Dictionary entry details 

• CHOLESTEROL (noun)

Sense 1

Meaning:

An animal sterol that is normally synthesized by the liver; the most abundant steroid in animal tissues

Classified under:

Nouns denoting substances

Synonyms:

cholesterin; cholesterol

Hypernyms ("cholesterol" is a kind of...):

steroid alcohol; sterol (any of a group of natural steroid alcohols derived from plants or animals; they are waxy insoluble substances)

Hyponyms (each of the following is a kind of "cholesterol"):

HDL cholesterol (the cholesterol in high-density lipoproteins; the 'good' cholesterol; a high level in the blood is thought to lower the risk of coronary artery disease)

LDL cholesterol (the cholesterol in low-density lipoproteins; the 'bad' cholesterol; a high level in the blood is thought to be related to various pathogenic conditions)

 Context examples 

A synthetic imidazole that inhibits hepatic cholesterol biosynthesis by inhibiting the cytochrome P450 enzyme lanosterol 14alpha-demethylase.

(Azalanstat, NCI Thesaurus)

A hydrochloride salt form of azacosterol, a sterol derivative of cholesterol that acts as a hypocholesteremic.

(Azacosterol Hydrochloride, NCI Thesaurus)

A sterol derivative of cholesterol with two nitrogen atoms replacing two carbon atoms that acts as a hypocholesteremic agent by blocking delta-24-reductase.

(Azacosterol, NCI Thesaurus)

This agent helps reduce LDL cholesterol and triglyceride levels, and is not associated with weight gain, and prevents the cardiovascular complications of diabetes.

(Metformin, NCI Thesaurus)

These molecules are part of many processes, including making cholesterol.

(Mevalonate pathway, NCI Dictionary)

This gene plays a role in the transport of both lipoproteins and cholesterol.

(MSR1 Gene, NCI Thesaurus)

An orally bioavailable inhibitor of acyl-Coenzyme A:cholesterol acyltransferase (ACAT) that prevents cholesterol deposition in the arterial wall.

(Avasimibe, NCI Thesaurus)

A drug used to lower the amount of cholesterol in the blood and to prevent stroke, heart attack, and angina (chest pain).

(Atorvastatin calcium, NCI Dictionary)

SR-45023A binds to hydroxyapatite crystals in the bone matrix where it inhibits enzymatic activity of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, which is required for the formation of mevalonate, the precursor of cholesterol.

(Apomine, NCI Thesaurus)

Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL thereby, producing an increase in serum HDL-cholesterol levels and a decrease in serum LDL-cholesterol levels.

(Anacetrapib, NCI Thesaurus)