English Dictionary

CENTROMERE

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 Dictionary entry overview: What does centromere mean? 

CENTROMERE (noun)
  The noun CENTROMERE has 1 sense:

1. a specialized condensed region of each chromosome that appears during mitosis where the chromatids are held together to form an X shapeplay

  Familiarity information: CENTROMERE used as a noun is very rare.


 Dictionary entry details 


CENTROMERE (noun)


Sense 1

Meaning:

A specialized condensed region of each chromosome that appears during mitosis where the chromatids are held together to form an X shape

Classified under:

Nouns denoting body parts

Synonyms:

centromere; kinetochore

Context example:

the centromere is difficult to sequence

Hypernyms ("centromere" is a kind of...):

anatomical structure; bodily structure; body structure; complex body part; structure (a particular complex anatomical part of a living thing and its construction and arrangement)

Holonyms ("centromere" is a part of...):

chromosome (a threadlike strand of DNA in the cell nucleus that carries the genes in a linear order)

Derivation:

centromeric (pertaining to the dense specialized portion of a chromosome to which the spindle attaches during mitosis)


 Context examples 


M1 is a rearranged long arm and centromere of chromosome 1 and the long arm of chromosome 3.

(HeLa, NCI Thesaurus)

An abnormal chromosome with two centromeres as opposed to the normal one centromere.

(Dicentric Chromosome, NCI Thesaurus)

This inversion is termed either pericentric, if it includes the centromere of a chromosome, or pancentric, if it excludes the centromere.

(Inversion Mutation Abnormality, NCI Thesaurus)

A chromosome inversion involving a segment that does not include the centromere.

(Paracentric Inversion, NCI Thesaurus)

A chromosome inversion involving a segment that includes the centromere.

(Pericentric Inversion, NCI Thesaurus)

They all have a short arm and long arm separated by a primary constriction called the centromere.

(Chromosome Arm, NCI Thesaurus)

The chromatids are held together at the centromere.

(Chromatid, NLM, Medical Subject Headings)

Aurora kinase B, a serine/threonine protein kinase that functions in the attachment of the mitotic spindle to the centromere, is overexpressed in a wide variety of cancer cell types.

(Barasertib, NCI Thesaurus)

A measurement of centromere B antibodies present in a sample.

(Centromere B Antibody Measurement, NCI Thesaurus)

A measurement of centromere B antibodies in a biological specimen.

(Centromere B Antibody Measurement, NCI Thesaurus/CDISC)



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