CEFUROXIME

Pronunciation (US):

(GB):

 Dictionary entry overview: What does cefuroxime mean? 

• CEFUROXIME (noun)
  The noun CEFUROXIME has 1 sense:

1. a cephalosporin that can be given parenterally (trade name Zinacef) or orally by tablets (trade name Ceftin); indicated for infections of the lungs or throat or ears or urinary tract or meninges

  Familiarity information: CEFUROXIME used as a noun is very rare.

 Dictionary entry details 

• CEFUROXIME (noun)

Sense 1

Meaning:

A cephalosporin that can be given parenterally (trade name Zinacef) or orally by tablets (trade name Ceftin); indicated for infections of the lungs or throat or ears or urinary tract or meninges

Classified under:

Nouns denoting man-made objects

Synonyms:

Ceftin; cefuroxime; Zinacef

Hypernyms ("cefuroxime" is a kind of...):

cephalosporin; Mefoxin (one of several broad spectrum antibiotic substances obtained from fungi and related to penicillin (trade names Mefoxin); addition of side chains has produced semisynthetic antibiotics with greater antibacterial activity)

 Context examples 

The sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity.

(Cefuroxime Sodium, NCI Thesaurus)

An ester prodrug of cefuroxime, a semisynthetic, broad-spectrum, beta-lactamase-resistant, second-generation cephalosporin with antibacterial activity.

(Cefuroxime Pivoxetil, NCI Thesaurus)

As a result, cefuroxime inhibits bacterial septum and cell wall synthesis formation.

(Cefuroxime Axetil, NCI Thesaurus)

Cefuroxime binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.

(Cefuroxime, NCI Thesaurus)

Cefuroxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane.

(Cefuroxime Axetil, NCI Thesaurus)

Cefuroxime sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of the cell wall.

(Cefuroxime Sodium, NCI Thesaurus)