English Dictionary

CASTRATION

Pronunciation (US): Play  (GB): Play

IPA (US): 

 Dictionary entry overview: What does castration mean? 

CASTRATION (noun)
  The noun CASTRATION has 3 senses:

1. neutering a male animal by removing the testiclesplay

2. surgical removal of the testes or ovaries (usually to inhibit hormone secretion in cases of breast cancer in women or prostate cancer in men)play

3. the deletion of objectionable parts from a literary workplay

  Familiarity information: CASTRATION used as a noun is uncommon.


 Dictionary entry details 


CASTRATION (noun)


Sense 1

Meaning:

Neutering a male animal by removing the testicles

Classified under:

Nouns denoting acts or actions

Synonyms:

castration; emasculation

Hypernyms ("castration" is a kind of...):

altering; fixing; neutering (the sterilization of an animal)

Derivation:

castrate (remove the testicles of a male animal)


Sense 2

Meaning:

Surgical removal of the testes or ovaries (usually to inhibit hormone secretion in cases of breast cancer in women or prostate cancer in men)

Classified under:

Nouns denoting acts or actions

Context example:

bilateral castration results in sterilization

Hypernyms ("castration" is a kind of...):

operation; surgery; surgical operation; surgical procedure; surgical process (a medical procedure involving an incision with instruments; performed to repair damage or arrest disease in a living body)

Derivation:

castrate (remove the ovaries of)


Sense 3

Meaning:

The deletion of objectionable parts from a literary work

Classified under:

Nouns denoting acts or actions

Synonyms:

castration; expurgation

Hypernyms ("castration" is a kind of...):

deletion (the act of deleting something written or printed)

Hyponyms (each of the following is a kind of "castration"):

bowdlerisation; bowdlerization (the act of deleting or modifying all passages considered to be indecent)

Derivation:

castrate (edit by omitting or modifying parts considered indelicate)


 Context examples 


This approach has been widely replaced by the use of either surgical (orchiectomy) or medical (LHRH agonist) castration.

(Flutamide-Leuprolide Regimen, NCI Thesaurus)

This agent reduces testosterone production to castration levels and may inhibit androgen receptor-positive tumor progression.

(Leuprolide, NCI Thesaurus)

This approach has been widely replaced by the use of surgical (orchiectomy) or medical (LHRH agonist) castration.

(Flutamide-Goserelin Regimen, NCI Thesaurus)

This may result in suppressed total serum testosterone to the levels observed in castration.

(Estrogen Receptor Agonist GTx-758, NCI Thesaurus)

Medical castration refers to the use of drugs to suppress the function of the ovaries or testicles.

(Castration, NCI Dictionary)

A well-known teratogen and carcinogen, diethylstilbestrol inhibits the hypothalamic-pituitary-gonadal axis, thereby blocking the testicular synthesis of testosterone, lowering plasma testosterone, and inducing a chemical castration.

(Diethylstilbestrol, NCI Thesaurus)



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