English Dictionary

CARBOXYLATE

Pronunciation (US): Play  (GB): Play

 Dictionary entry overview: What does carboxylate mean? 

CARBOXYLATE (verb)
  The verb CARBOXYLATE has 1 sense:

1. treat (a chemical compound) with carboxyl or carboxylic acidplay

  Familiarity information: CARBOXYLATE used as a verb is very rare.


 Dictionary entry details 


CARBOXYLATE (verb)

 Conjugation: 
Present simple: I / you / we / they carboxylate  Listen to US pronunciation  Listen to GB pronunciation ... he / she / it carboxylates  Listen to US pronunciation  Listen to GB pronunciation
Past simple: carboxylated  Listen to US pronunciation  Listen to GB pronunciation
Past participle: carboxylated  Listen to US pronunciation  Listen to GB pronunciation
-ing form: carboxylating  Listen to US pronunciation  Listen to GB pronunciation


Sense 1

Meaning:

Treat (a chemical compound) with carboxyl or carboxylic acid

Classified under:

Verbs of size, temperature change, intensifying, etc.

Hypernyms (to "carboxylate" is one way to...):

process; treat (subject to a process or treatment, with the aim of readying for some purpose, improving, or remedying a condition)

Domain category:

chemical science; chemistry (the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions)

Sentence frame:

Somebody ----s something


 Context examples 


Nicotinate-nucleotide pyrophosphorylase [carboxylating] (297 aa, ~31 kDa) is encoded by the human QPRT gene.

(Nicotinate-Nucleotide Pyrophosphorylase [Carboxylating], NCI Thesaurus)

The hydrochloride salt form of fexofenadine, a carboxylated metabolic derivative of terfenadine and third generation selective histamine H1-receptor antagonist with antihistaminic and non-sedative effects.

(Fexofenadine Hydrochloride, NCI Thesaurus)

These modified glutamyl residues are absent because of either vitamin K deficiency or inhibition of vitamin K activity that, in turn, inhibits the enzyme that carboxylates these residues, vitamin K-dependent gamma-carboxylase.

(Des-Gamma Carboxyprothrombin, NCI Thesaurus)

Camptothecin readily undergoes hydrolysis at physiological pH, changing its conformation from the active, S-configured lactone structure to an inactive carboxylate form.

(Camptothecin-20(S)-O-Propionate Hydrate, NCI Thesaurus)

The addition involves cleavage and addition to the free thiol group of cysteine moiety, and methylation of the free carboxylate group on the protein's carboxyl terminus.

(Farnesylation Process, NCI Thesaurus)

A targeted antibody payload (TAP)-based immunoconjugate consisting of a human monoclonal antibody directed against the epidermal growth factor receptor (EGFR) conjugated, via a nonreducible thioether linker (succinimidyl trans-4-(maleimidylmethyl)cyclohexane-1-carboxylate or SMCC), to the cytotoxic agent maytansinoid mertansine (DM1), with potential antineoplastic activity.

(Anti-EGFR TAP Antibody-drug Conjugate IMGN289, NCI Thesaurus)



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