BETA-LACTAMASE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does beta-lactamase mean? 

• BETA-LACTAMASE (noun)
  The noun BETA-LACTAMASE has 1 sense:

1. enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic

  Familiarity information: BETA-LACTAMASE used as a noun is very rare.

 Dictionary entry details 

• BETA-LACTAMASE (noun)

Sense 1

Meaning:

Enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic

Classified under:

Nouns denoting substances

Synonyms:

beta-lactamase; penicillinase

Hypernyms ("beta-lactamase" is a kind of...):

enzyme (any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions)

 Context examples 

The disodium salt form of carbenicillin, a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity.

(Carbenicillin Disodium, NCI Thesaurus)

A broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity.

(Carbenicillin, NCI Thesaurus)

Methicillin sodium is active against beta-lactamase producing staphylococci.

(Methicillin Sodium, NCI Thesaurus)

A synthetic inhibitor of beta-lactamases produced by both gram-positive and gram-negative bacteria.

(Brobactam, NCI Thesaurus)

Carumonam has high resistance to beta-lactamases and activity against aerobic gram-negative bacteria.

(Carumonam, NCI Thesaurus)

Semisynthetic wide-spectrum cephalosporin with prolonged action, probably due to beta-lactamase resistance.

(Cefamandole, NLM, Medical Subject Headings)

Cefodizime has broad-spectrum activity and is stable to most beta-lactamases.

(Cefodizime, NCI Thesaurus)

Stable in the presence of a variety of beta-lactamases, this agent is more active against gram-negative bacteria and less active against gram-positive bacteria compared to second-generation cephalosporins.

(Cefixime, NCI Thesaurus)

The 7-alpha-methoxy group and the para-hydroxyphenylmalonyl group increases the stability of this agent against beta-lactamases.

(Moxalactam, NCI Thesaurus)

They are substrates for and may act as inhibitors of bacterial beta-lactamases.

(Beta-Lactam Antibiotic, NLM, Medical Subject Headings)