BENZOQUINONE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does benzoquinone mean? 

• BENZOQUINONE (noun)
  The noun BENZOQUINONE has 1 sense:

1. any of a class of aromatic yellow compounds including several that are biologically important as coenzymes or acceptors or vitamins; used in making dyes

  Familiarity information: BENZOQUINONE used as a noun is very rare.

 Dictionary entry details 

• BENZOQUINONE (noun)

Sense 1

Meaning:

Any of a class of aromatic yellow compounds including several that are biologically important as coenzymes or acceptors or vitamins; used in making dyes

Classified under:

Nouns denoting substances

Synonyms:

benzoquinone; quinone

Hypernyms ("benzoquinone" is a kind of...):

chemical compound; compound ((chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight)

Hyponyms (each of the following is a kind of "benzoquinone"):

coenzyme Q; ubiquinone (any of several quinones found in living cells and that function as coenzymes that transfer electrons from one molecule to another in cell respiration)

 Context examples 

An extract of fermented wheat germ containing a concentrated, standardized amount of methoxy-substituted benzoquinones with immunomodulatory and potential antineoplastic activities.

(Fermented Wheat Germ Extract, NCI Thesaurus)

A benzoquinone antineoplastic antibiotic isolated from the bacterium Streptomyces hygroscopicus.

(Geldanamycin, NCI Thesaurus)

An analogue of the antineoplastic benzoquinone antibiotic geldanamycin.

(Alvespimycin, NCI Thesaurus)

A naturally occurring benzoquinone important in electron transport in mitochondrial membranes.

(coenzyme Q10, NCI Thesaurus)

An antineoplastic antibiotic that is structurally similar to the benzoquinone ansamycin antibiotic geldanamycin.

(Anthracycline Antineoplastic Antibiotic, NCI Thesaurus)

An antineoplastic antibiotic of macrocyclic benzoquinone isolated from the bacterial genus Streptomyces.

(Ansamycin Antineoplastic Antibiotic, NCI Thesaurus)

The hydrochloride salt of alvespimycin, an analogue of the antineoplastic benzoquinone antibiotic geldanamycin.

(Alvespimycin Hydrochloride, NCI Thesaurus)

For instance, acetaminophen, one of the most commonly used drug, is toxic in high doses due to the activation of CAR and the drug's subsequent conversion to acetyl-p-benzoquinone imine (NAPQI) by CYP1A2, CYP2E1 and CYP3A.

(Lipid Metabolism and Toxicity Pathway, NCI Thesaurus/BIOCARTA)

The benzoquinones may contribute to the immunomodulatory effects of FWGE, down-regulating major histocompatibility complex class I (MHC-1) protein on the surface of cancer cells, allowing natural killer (NK) cell surveillance; and up-regulating the expression of intracellular adhesion molecule 1 (ICAM-1) on tumor endothelial cells.

(Fermented Wheat Germ Extract, NCI Thesaurus)