English Dictionary

BASOPHILIA

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 Dictionary entry overview: What does basophilia mean? 

BASOPHILIA (noun)
  The noun BASOPHILIA has 1 sense:

1. the tendency of cells to stain with basic dyesplay

  Familiarity information: BASOPHILIA used as a noun is very rare.


 Dictionary entry details 


BASOPHILIA (noun)


Sense 1

Meaning:

The tendency of cells to stain with basic dyes

Classified under:

Nouns denoting attributes of people and objects

Context example:

cytoplasmic basophilia

Hypernyms ("basophilia" is a kind of...):

stainability ((cytology) the capacity of cells or cell parts to stain specifically with certain dyes)

Derivation:

basophilic (staining readily with basic dyes)


 Context examples 


It is characterized by the presence of hepatocytes with decreased cell volume, increased nuclear/cytoplasmic ratio, basophilia, mild nuclear pleomorphism, and hyperchromasia.

(Hepatocellular Small Cell Change, NCI Thesaurus)

This rearrangement was observed in one patient with refractory anemia with excess blasts with basophilia, one patient with acute myelogenous leukemia with eosinophilia, and one patient with acute eosinophilic leukemia

(ETV6/ACSL6 Fusion Gene, NCI Thesaurus)

It is often associated with multilineage dysplasia and basophilia.

(Acute Myeloid Leukemia with t(6;9)(p23;q34); DEK-NUP214, NCI Thesaurus)

A chromosomal translocation t(5;12)(q31;p13) of this gene with the ETV6 gene is associated with myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia.

(ACSL6 wt Allele, NCI Thesaurus)

In one patient with refractory anemia with excess blasts with basophilia, this rearrangement fused exon 19 of the ACSL6 gene with a site within exon 1 of the ETV6 gene and could result in the production of a fusion protein.

(ACSL6/ETV6 Fusion Gene, NCI Thesaurus)



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