B CELL

Pronunciation (US):

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 Dictionary entry overview: What does B cell mean? 

• B CELL (noun)
  The noun B CELL has 1 sense:

1. a lymphocyte derived from bone marrow that provides humoral immunity; it recognizes free antigen molecules in solution and matures into plasma cells that secrete immunoglobulin (antibodies) that inactivate the antigens

  Familiarity information: B CELL used as a noun is very rare.

 Dictionary entry details 

• B CELL (noun)

Sense 1

Meaning:

A lymphocyte derived from bone marrow that provides humoral immunity; it recognizes free antigen molecules in solution and matures into plasma cells that secrete immunoglobulin (antibodies) that inactivate the antigens

Classified under:

Nouns denoting body parts

Synonyms:

B cell; B lymphocyte

Hypernyms ("B cell" is a kind of...):

lymph cell; lymphocyte (an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection)

 Context examples 

This allele, which encodes musculin protein, is involve in both the modulation of transcription by RNA polymerase II and antigen-dependent differentiation in B cells.

(MSC wt Allele, NCI Thesaurus)

A lymphocyte derived most often from a pre-germinal center B cell, less often from a post-germinal center B cell.

(Monocytoid B-Lymphocyte, NCI Thesaurus)

This ultimately leads to the proliferation of human B cells, activation of natural killer (NK) cells and dendritic cells (DCs), an increase in HLA-I and HLA-II expression and activation of CD8-lymphocytes.

(Multi-subtype Natural Human Leukocyte Interferon Alpha, NCI Thesaurus)

Natural killer cells are large granular lymphocytes which do not express markers of either T or B cell lineage.

(Murine Natural Killer Cells, NCI Thesaurus)

They do not express markers of either T or B cell lineage.

(Natural killer cell, NCI Thesaurus)

Monoclonal antibody LYM-2 may induce cell-mediated lysis of neoplastic human B cells.

(Monoclonal Antibody Lym-2, NCI Thesaurus)

Collaborators from the Institute for Research in Biomedicine in Switzerland then cloned antibody-producing B cells from the survivor to make mAbs for potential use as a therapeutic for Ebola infection.

(Experimental Ebola antibody protects monkeys, NIH)

When the B cell receptor immunoglobulin binds antigen, that cell is activated to proliferate and create plasma cells secreting immunoglobulins to bind that specific antigen.

(Antigen Dependent B Cell Activation Pathway, NCI Thesaurus/BIOCARTA)

A murine monoclonal antibody directed against CD20, a cross-membrane ion channel phosphoprotein expressed by B cells, with potential antineoplastic activity.

(Monoclonal Antibody 1F5, NCI Thesaurus)

Any process that decreases the frequency, rate or extent of apoptosis in B cells, T cells or natural killer cells.

(Negative Regulation of Lymphocyte Apoptotic Process, NCI Thesaurus)