ASPARTIC ACID

Pronunciation (US):

(GB):

 Dictionary entry overview: What does aspartic acid mean? 

• ASPARTIC ACID (noun)
  The noun ASPARTIC ACID has 1 sense:

1. a crystalline amino acid found in proteins and occurring naturally in sugar beets and sugar cane

  Familiarity information: ASPARTIC ACID used as a noun is very rare.

 Dictionary entry details 

• ASPARTIC ACID (noun)

Sense 1

Meaning:

A crystalline amino acid found in proteins and occurring naturally in sugar beets and sugar cane

Classified under:

Nouns denoting substances

Hypernyms ("aspartic acid" is a kind of...):

amino acid; aminoalkanoic acid (organic compounds containing an amino group and a carboxylic acid group)

 Context examples 

This agent may also exert some anticholinergic effect through inhibition of N-methyl-D-aspartic acid (NMDA) receptor-mediated stimulation of acetylcholine, resulting in antihyperalgesia.

(Amantadine, NCI Thesaurus)

In contrast, this agent also acts as a co-agonist, along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

(Glycine, NCI Thesaurus)

Glutamatergic-mediated nitric oxide (NO) production occurs via the N-methyl-D-aspartic acid (NMDA) postsynaptic density protein 95 (PSD95)-neuronal nitric oxide synthase (NOS1) ternary complex.

(Nitric Oxide Signaling Pathway, NCI Thesaurus/BIOCARTA)

Aspartic acid also serves as a neurotransmitter.

(Aspartic Acid, NCI Thesaurus)

They are specific for aspartic acid at the P1 position and are divided into two classes based on the lengths of their N-terminal pro-domains.

(Caspase, NCI Thesaurus)

Asparaginase hydrolyzes L-asparagine to L-aspartic acid and ammonia, thereby depleting leukemic cells of asparagine and blocking protein synthesis and tumor cell proliferation, especially in the G1 phase of the cell cycle.

(asparaginase Erwinia chrysanthemi, NCI Thesaurus)

A non-essential amino acid in humans, Asparagine is a beta-amido derivative of aspartic acid and plays an important role in the biosynthesis of glycoproteins and other proteins.

(Asparagine, NCI Thesaurus)

Upon intravenous administration of pegylated recombinant L-asparaginase Erwinia chrysanthemi, asparaginase hydrolyzes L-asparagine to L-aspartic acid and ammonia, thereby depleting cancer cells of asparagine thus blocking protein synthesis and tumor cell proliferation.

(Pegylated Recombinant L-asparaginase Erwinia chrysanthemi, NCI Thesaurus)

In (H115D)VHL35 peptide, histidine is substituted for an aspartic acid in position 115.

((H115D)VHL35 Peptide, NCI Thesaurus)

Asparaginase hydrolyzes L-asparagine to L-aspartic acid and ammonia, thereby depleting these cells of asparagine and blocking protein synthesis and tumor cell proliferation, especially in the G1 phase of the cell cycle.

(Pegaspargase, NCI Thesaurus)