English Dictionary

APOPTOSIS

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 Dictionary entry overview: What does apoptosis mean? 

APOPTOSIS (noun)
  The noun APOPTOSIS has 1 sense:

1. a type of cell death in which the cell uses specialized cellular machinery to kill itself; a cell suicide mechanism that enables metazoans to control cell number and eliminate cells that threaten the animal's survivalplay

  Familiarity information: APOPTOSIS used as a noun is very rare.


 Dictionary entry details 


APOPTOSIS (noun)


Sense 1

Meaning:

A type of cell death in which the cell uses specialized cellular machinery to kill itself; a cell suicide mechanism that enables metazoans to control cell number and eliminate cells that threaten the animal's survival

Classified under:

Nouns denoting natural phenomena

Synonyms:

apoptosis; caspase-mediated cell death; programmed cell death

Hypernyms ("apoptosis" is a kind of...):

cell death; necrobiosis ((physiology) the normal degeneration and death of living cells (as in various epithelial cells))


 Context examples 


An alkylating agent that bind to the DNA minor groove in a sequence-specific manner and form covalent adducts with adenines, resulting in the inhibition of DNA replication and induction of apoptosis.

(Adozelesin, NCI Thesaurus)

These cells contribute to wound repair through a variety of mechanisms by promoting blood vessel growth and blocking apoptosis.

(Adipose-Derived Regenerative Cells, NCI Thesaurus)

This protein is involved in apoptosis.

(Melanoma-Associated Antigen D1, NCI Thesaurus)

This results in the inhibition of DNA and RNA synthesis and the induction of apoptosis, thereby inhibiting tumor cell proliferation.

(Melphalan-Flufenamide Prodrug, NCI Thesaurus)

This agent inhibits tumor cell growth by inducing apoptosis and cell cycle arrest.

(Menatetrenone, NCI Thesaurus)

As time passed, the genetic damage increased, and cells underwent apoptosis (non-inflammatory cell death) and necrosis (cell death that leads to inflammation)”.

(Lung damage from agricultural fires probed, SciDev.Net)

AIF (apoptosis inducing factor) is another mitochondrial factor that is released into the cytoplasm to induce apoptosis.

(Mitochondria in Apoptotic Signaling Pathway, NCI Thesaurus/BIOCARTA)

This protein plays a role in serine/threonine phosphorylation, apoptosis and toll-like receptor signaling.

(Mitogen-Activated Protein Kinase 8, NCI Thesaurus)

After intratumoral injection and adenovector-mediated gene transfer of MDA7 into tumor cells, the expressed MDA7 transgene may inhibit tumor cell proliferation and induce tumor cell apoptosis.

(Adenovector Encoding MDA7, NCI Thesaurus)

May induce apoptosis through the TNF pathway.

(Adenovirus 5-CD40 Ligand, NCI Thesaurus)



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