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 Dictionary entry overview: What does antagonistic mean? 

ANTAGONISTIC (adjective)
  The adjective ANTAGONISTIC has 5 senses:

1. indicating opposition or resistance
2. characterized by antagonism or antipathy
3. arousing animosity or hostility
4. used especially of drugs or muscles that counteract or neutralize each other's effect
5. incapable of harmonious association

  Familiarity information: ANTAGONISTIC used as an adjective is common.

 Dictionary entry details 

ANTAGONISTIC (adjective)

Sense 1antagonistic [BACK TO TOP]


Indicating opposition or resistance


antagonistic; counter


negative (characterized by or displaying negation or denial or opposition or resistance; having no positive features)

Sense 2antagonistic [BACK TO TOP]


Characterized by antagonism or antipathy


antagonistic; antipathetic; antipathetical

Context examples:

slaves antagonistic to their masters / antipathetic factions within the party


hostile (characterized by enmity or ill will)

Sense 3antagonistic [BACK TO TOP]


Arousing animosity or hostility

Context examples:

his antagonistic brusqueness / Europe was antagonistic to the Unites States


alienating (causing hostility or loss of friendliness)


conciliatory (intended or likely to overcome animosity or hostility)

Sense 4antagonistic [BACK TO TOP]


Used especially of drugs or muscles that counteract or neutralize each other's effect


incompatible; antagonistic


antacid (acting to neutralize acid (especially in the stomach))

antiphlogistic (counteracting inflammation)


synergistic (used especially of drugs or muscles that work together so the total effect is greater than the sum of the two (or more))

Sense 5antagonistic [BACK TO TOP]


Incapable of harmonious association


incompatible (not compatible)

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