AMPHOTERICIN

Pronunciation (US):

(GB):

 Dictionary entry overview: What does amphotericin mean? 

• AMPHOTERICIN (noun)
  The noun AMPHOTERICIN has 1 sense:

1. an antibiotic and antifungal agent

  Familiarity information: AMPHOTERICIN used as a noun is very rare.

 Dictionary entry details 

• AMPHOTERICIN (noun)

Sense 1

Meaning:

An antibiotic and antifungal agent

Classified under:

Nouns denoting man-made objects

Hypernyms ("amphotericin" is a kind of...):

antibiotic; antibiotic drug (a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections)

 Context examples 

Amphotericin B binds to ergosterol, an essential component of the fungal cell membrane, and alters cell membrane integrity, resulting in leakage of intracellular components and cell rupture.

(Liposomal Amphotericin B, NCI Thesaurus)

The deoxycholate salt of amphotericin B, a polyene antifungal antibiotic produced by Streptomyces nodosus, with antifungal activity.

(Amphotericin B Deoxycholate, NCI Thesaurus)

The researchers noted that amphotericin can be delivered directly to the lungs to avoid common side effects.

(Scientists find new approach that shows promise for treating cystic fibrosis, National Institutes of Health)

Amphotericin B binds to ergosterol, an essential component of the fungal cell membrane, thereby causing depolarization of the membrane and altering cell membrane permeability.

(amphotericin B, NCI Thesaurus)

Liposome encapsulated macrolide antifungal antibiotic amphotericin B. Amphotericin B binds to ergosterol altering cell membrane integrity with subsequent cell death.

(Amphotericin B Liposomal, NCI Thesaurus)

Amphotericin B binds to ergosterol, an essential component of the fungal cell membrane.

(Amphotericin B Deoxycholate, NCI Thesaurus)

Compared to amphotericin B alone, liposomal delivery of amphotericin B allows for a greater drug concentration in target tissues while decreasing systemic side effects.

(Liposomal Amphotericin B, NCI Thesaurus)

The really exciting news is that amphotericin is a medicine that’s already approved and available on the market.

(Scientists find new approach that shows promise for treating cystic fibrosis, National Institutes of Health)

A liposome-encapsulated formulation of the polyene antifungal antibiotic amphotericin B produced by the bacterium Streptomyces nodosus with antifungal activity.

(Liposomal Amphotericin B, NCI Thesaurus)

But amphotericin has the potential to work regardless of the kind of mutation, and even when the protein is missing.

(Scientists find new approach that shows promise for treating cystic fibrosis, National Institutes of Health)