ADENOSINE DEAMINASE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does adenosine deaminase mean? 

• ADENOSINE DEAMINASE (noun)
  The noun ADENOSINE DEAMINASE has 1 sense:

1. an enzyme found in mammals that can catalyze the deamination of adenosine into inosine and ammonia

  Familiarity information: ADENOSINE DEAMINASE used as a noun is very rare.

 Dictionary entry details 

• ADENOSINE DEAMINASE (noun)

Sense 1

Meaning:

An enzyme found in mammals that can catalyze the deamination of adenosine into inosine and ammonia

Classified under:

Nouns denoting substances

Synonyms:

ADA; adenosine deaminase

Context example:

the gene encoding ADA was one of the earlier human genes to be isolated and cloned for study

Hypernyms ("adenosine deaminase" is a kind of...):

enzyme (any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions)

 Context examples 

Because it can be converted to an inactive metabolite by adenosine deaminase, this agent must be administered with an adenosine deaminase inhibitor in order to be effective.

(Cordycepin, NCI Thesaurus)

Because it is converted to an inactive metabolite by adenosine deaminase, this agent must be administered with an adenosine deaminase inhibitor in order to be effective.

(Cordycepin Triphosphate, NCI Thesaurus)

Nelarabine is demethoxylated by adenosine deaminase to become biologically active 9-beta-D-arabinosylguanine (ara-G); ara-G incorporates into DNA, thereby inhibiting DNA synthesis and inducing an S phase-dependent apoptosis of tumor cells.

(Nelarabine, NCI Thesaurus)

It is a type of adenosine deaminase inhibitor.

(Nipent, NCI Dictionary)

Because this agent is resistant to adenosine deaminase, an enzyme that inactivates some antineoplastic agents, it is selectively toxic to lymphocytes and monocytes which exhibit little deoxynucleotide deaminase activity.

(Cladribine, NCI Thesaurus)

Any substance that inhibits adenosine deaminase, an enzyme involved with the degradation of adenine in purine metabolism and that acts as a positive regulator of T-cell coactivation.

(Adenosine Deaminase Inhibitor, NCI Thesaurus)

This allele, which encodes adenosine deaminase protein, is involved in the hydrolysis of adenosine to inosine.

(ADA wt Allele, NCI Thesaurus)

An autosomal recessive deficiency of the purine salvage enzyme adenosine deaminase which results in Severe Combined Immunodeficiency Disease (SCID).

(Adenosine Deaminase Deficiency, NCI Thesaurus)

Adenosine deaminase (363 aa, ~41 kDa) is encoded by the human ADA gene.

(Adenosine Deaminase, NCI Thesaurus)

T cells harvested from a patient with adenosine deaminase (ADA) deficiency and transduced with a vector containing the gene for ADA.

(ADA Transduced T Cell, NCI Thesaurus)