ABERRANT

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does aberrant mean? 

• ABERRANT (noun)
  The noun ABERRANT has 1 sense:

1. one whose behavior departs substantially from the norm of a group

  Familiarity information: ABERRANT used as a noun is very rare.

• ABERRANT (adjective)
  The adjective ABERRANT has 1 sense:

1. markedly different from an accepted norm

  Familiarity information: ABERRANT used as an adjective is very rare.

 Dictionary entry details 

• ABERRANT (noun)

Sense 1

Meaning:

One whose behavior departs substantially from the norm of a group

Classified under:

Nouns denoting people

Hypernyms ("aberrant" is a kind of...):

anomaly; unusual person (a person who is unusual)

Derivation:

aberrant (markedly different from an accepted norm)

aberrate (diverge from the expected)

• ABERRANT (adjective)

Sense 1

Meaning:

Markedly different from an accepted norm

Synonyms:

aberrant; deviant; deviate

Context example:

deviant ideas

Similar:

abnormal; unnatural (not normal; not typical or usual or regular or conforming to a norm)

Derivation:

aberrance; aberrancy (a state or condition markedly different from the norm)

aberrant (one whose behavior departs substantially from the norm of a group)

 Context examples 

MUC1 antigen, a membrane-bound glycoprotein expressed by most glandular and ductal epithelial cells, is overexpressed in an aberrant or deglycosylated form in various cancers such as those of the breast, prostate, and ovary.

(MUC1-KLH Conjugate Vaccine, NCI Thesaurus)

Aberrant expression is associated with prostate cancer and hepatocellular carcinomas.

(MTDH wt Allele, NCI Thesaurus)

MUC1 antigen, a membrane-bound glycoprotein expressed by most glandular and ductal epithelial cells, is overexpressed as an aberrant or deglycosylated form in various cancers such as breast, prostate and ovarian cancers.

(MUC1-KLH Vaccine/QS21, NCI Thesaurus)

These aberrant genes are activated by mutations or amplification, resulting in overexpression of the protein products.

(MYC-Family Oncogene, NCI Thesaurus)

Aberrant expression of the gene may be involved in tumor initiation, and progression.

(NEDD9 wt Allele, NCI Thesaurus)

A group of rare myeloid and lymphoid neoplasms characterized by rearrangement of the PDGFRA, PDGFRB, or FGFR1 genes, resulting in the formation of fusion transcripts and aberrant tyrosine kinase activity.

(Myeloid and Lymphoid Neoplasms with Eosinophilia and Abnormalities of PDGFRA, PDGFRB, or FGFR1, NCI Thesaurus)

Aberrant expression of the gene is observed in T-cell leukemias bearing a t(X;14) translocation.

(MTCP1 wt Allele, NCI Thesaurus)

Aberrant Snail expression results in loss of expression of the cell adhesion molecule E-cadherin, an event associated with changes in epithelial architecture and invasive growth.

(MTA3 Pathway, NCI Thesaurus/BIOCARTA)

Aberrant alleles are associated with colon, endometrial and stomach cancers.

(MLH1 wt Allele, NCI Thesaurus)

Aberrant expression of the gene is associated with multiple myeloma.

(MIR194-1 wt Allele, NCI Thesaurus)